Anti-Idiotype DNA Aptamer Affinity Purification–High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab

Anti-Idiotype DNA Aptamer Affinity Purification–High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab

This study presents a simple, accurate, and selective bioanalytical method of bevacizumab detection from plasma samples based on aptamer affinity purification⁻high-temperature reversed-phased liquid chromatography (HT-RPLC) with fluorescence detection. Bevacizumab in plasma samples was pur...

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Bibliographic Details
Main Authors: Tomohiro Yamada, Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Hideki Hayashi, Hajime Mizuno, Daiki Tsuji, Keisuke Yamamoto, Kunihiko Itoh, Toshimasa Toyo’oka, Kazunori Ikebukuro, Kenichiro Todoroki
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
aptamer affinity purification
high-temperature reversed-phase liquid chromatography
immunoaffinity purification
bevacizumab
Online Access:https://www.mdpi.com/1420-3049/24/5/857

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https://www.mdpi.com/1420-3049/24/5/857

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