Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling

Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling

Staphylococcus aureus triggers inflammation through inflammasome activation and recruitment of neutrophils, responses that are critical for pathogen clearance but are associated with substantial tissue damage. We postulated that necroptosis, cell death mediated by the RIPK1/RIPK3/MLKL pathway, would...

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Bibliographic Details
Main Authors: Kipyegon Kitur, Sarah Wachtel, Armand Brown, Matthew Wickersham, Franklin Paulino, Hernán F. Peñaloza, Grace Soong, Susan Bueno, Dane Parker, Alice Prince
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716309573

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http://www.sciencedirect.com/science/article/pii/S2211124716309573

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