Lemon Exosome-like Nanoparticles-Manipulated Probiotics Protect Mice from C. diff Infection

Summary: Clostridioides difficile (C. diff) is the leading cause of antibiotic-associated colitis. Here, we report that lemon exosome-like nanoparticles (LELNs) manipulated probiotics to inhibit C. diff infection (CDI). LELN-manipulated Lactobacillus rhamnosus GG (LGG) and Streptococcus thermophilus...

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Bibliographic Details
Main Authors: Chao Lei, Jingyao Mu, Yun Teng, Liqing He, Fangyi Xu, Xiangcheng Zhang, Kumaran Sundaram, Anil Kumar, Mukesh K. Sriwastva, Matthew B. Lawrenz, Lifeng Zhang, Jun Yan, Wenke Feng, Craig J. McClain, Xiang Zhang, Huang-Ge Zhang
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S258900422030763X