High-fat, high-sugar diet induces splenomegaly that is ameliorated with exercise and genistein treatment

High-fat, high-sugar diet induces splenomegaly that is ameliorated with exercise and genistein treatment

Abstract Objective We tested the effect of exercise training and genistein treatment on splenomegaly in mice fed a high-fat, high-sugar diet (HFSD). Results Male and female C57BL6 mice fed HFSD containing 60% fat along with drinking water containing 42 g/L sugar (55% sucrose/45% fructose) for 12 wee...

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Bibliographic Details
Main Authors: Levi Buchan, Chaheyla R. St. Aubin, Amy L. Fisher, Austin Hellings, Monica Castro, Layla Al-Nakkash, Tom L. Broderick, Jeffrey H. Plochocki
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Research Notes
Subjects:
High-fat diet
High-sugar diet
Spleen
Exercise
Genistein
Online Access:http://link.springer.com/article/10.1186/s13104-018-3862-z

Internet

http://link.springer.com/article/10.1186/s13104-018-3862-z

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