Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice

Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice

In the present study, we investigated the role of Nrf2 in airway immune responses induced by diesel exhaust (DE) inhalation in mice. C57BL/6J <i>Nrf2</i><sup>+/+</sup> and <i>Nrf2</i><sup>−/−</sup> mice were exposed to DE or clean air for 8 h/day and 6...

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Bibliographic Details
Main Authors: Ying-Ji Li, Takako Shimizu, Yusuke Shinkai, Tomomi Ihara, Masao Sugamata, Katsuhito Kato, Maiko Kobayashi, Yukiyo Hirata, Hirofumi Inagaki, Makoto Uzuki, Toshio Akimoto, Masakazu Umezawa, Ken Takeda, Arata Azuma, Masayuki Yamamoto, Tomoyuki Kawada
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomedicines
Subjects:
oxidative stress/anti-oxidative stress
immune response
macrophage
neutrophils
lung diseases
Online Access:https://www.mdpi.com/2227-9059/8/10/443

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https://www.mdpi.com/2227-9059/8/10/443

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