Detection of Phosphorylated Alpha-Synuclein in the Muscularis Propria of the Gastrointestinal Tract Is a Sensitive Predictor for Parkinson’s Disease

Background. Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor impairments, including constipation. Lewy bodies and neurites, the pathological hallmarks of PD, are found in the enteric nervous system (ENS) as well as the central nervous system. Constipation...

Full description

Bibliographic Details
Main Authors: Goichi Beck, Yumiko Hori, Yoshito Hayashi, Eiichi Morii, Tetsuo Takehara, Hideki Mochizuki
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2020/4687530