A multi-stage association study of plasma cytokines identifies osteopontin as a biomarker for acute coronary syndrome risk and severity

Abstract Cytokines play a critical role in the pathogenesis and development of cardiovascular diseases. However, data linking cytokines to risk and severity of acute coronary syndrome (ACS) are still limited. We measured plasma profile of 280 cytokines using a quantitative protein microarray in 12 A...

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Bibliographic Details
Main Authors: Kuai Yu, Binyao Yang, Haijing Jiang, Jun Li, Kai Yan, Xuezhen Liu, Lue Zhou, Handong Yang, Xiulou Li, Xinwen Min, Ce Zhang, Xiaoting Luo, Wenhua Mei, Shunchang Sun, Liyun Zhang, Xiang Cheng, Meian He, Xiaomin Zhang, An Pan, Frank B. Hu, Tangchun Wu
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-41577-4