Analysis and control of an age-structured HIV-1 epidemic model with different transmission mechanisms

Abstract In this paper, we propose a within-host HIV-1 epidemic model with cell-to-virus and cell-to-cell transmission. By mathematical analysis, we obtain the basic reproduction number R 0 $\mathcal {R}_{0}$ , which determines the viral persistence and the basic reproduction number R 0 cc $\mathcal...

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Bibliographic Details
Main Authors: Xiaoyan Wang, Junyuan Yang, Fei Xu
Format: Article
Language:English
Published: SpringerOpen 2018-01-01
Series:Advances in Difference Equations
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13662-017-1455-0