Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures

Abstract We are now in an era of molecular medicine, where specific DNA alterations can be used to identify patients who will respond to specific drugs. However, there are only a handful of clinically used predictive biomarkers in oncology. Herein, we describe an approach utilizing in vitro DNA and...

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Bibliographic Details
Main Authors: Nicholas R. Rydzewski, Erik Peterson, Joshua M. Lang, Menggang Yu, S. Laura Chang, Martin Sjöström, Hamza Bakhtiar, Gefei Song, Kyle T. Helzer, Matthew L. Bootsma, William S. Chen, Raunak M. Shrestha, Meng Zhang, David A. Quigley, Rahul Aggarwal, Eric J. Small, Daniel R. Wahl, Felix Y. Feng, Shuang G. Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-021-00239-z