Dual RNase and β-lactamase Activity of a Single Enzyme Encoded in Archaea

Dual RNase and β-lactamase Activity of a Single Enzyme Encoded in Archaea

β-lactam antibiotics have a well-known activity which disturbs the bacterial cell wall biosynthesis and may be cleaved by β-lactamases. However, these drugs are not active on archaea microorganisms, which are naturally resistant because of the lack of β-lactam target in their cell wall. Here, we des...

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Bibliographic Details
Main Authors: Seydina M. Diene, Lucile Pinault, Nicholas Armstrong, Said Azza, Vivek Keshri, Saber Khelaifia, Eric Chabrière, Gustavo Caetano-Anolles, Jean-Marc Rolain, Pierre Pontarotti, Didier Raoult
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Life
Subjects:
archaea
metallo-β-lactamases
ribonucleases
glyoxalases
common ancestor sequence
core genes
Online Access:https://www.mdpi.com/2075-1729/10/11/280

Internet

https://www.mdpi.com/2075-1729/10/11/280

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