Exosomal circEIF3K from cancer-associated fibroblast promotes colorectal cancer (CRC) progression via miR-214/PD-L1 axis

Abstract Background Tumor microenvironment (e.g., cancer-associated fibroblast) plays a key role in cancer tumorigenesis and metastasis. However, the detailed mechanism of whether hypoxia promotes CRC progression via tumor microenvironment remains unclear. Methods In this study, circEIF3K exosome wa...

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Bibliographic Details
Main Authors: Kaihua Yang, Jie Zhang, Chuanqing Bao
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-08669-9