Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm

Myomerger mediates the transition from the early hemifusion stage to complete fusion during the formation of multinucleated muscle cells. Here, authors use theoretical modeling and cell fusion experiments to show that Myomerger promotes a fusion pore by coupling the elastic stresses of the proximal...

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Bibliographic Details
Main Authors: Gonen Golani, Evgenia Leikina, Kamran Melikov, Jarred M. Whitlock, Dilani G. Gamage, Gracia Luoma-Overstreet, Douglas P. Millay, Michael M. Kozlov, Leonid V. Chernomordik
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20804-x