Anti-inflammatory Activity of the Protein Z-Dependent Protease Inhibitor

Anti-inflammatory Activity of the Protein Z-Dependent Protease Inhibitor

The protein Z (PZ)-dependent plasma protease inhibitor (ZPI) is a glycoprotein that inhibits factor XIa and, in the presence of PZ, FXa. Recently, ZPI has been shown to be an acute-phase protein (APP). As usually APPs downregulate the harmful effects of inflammation, we tested whether ZPI could modu...

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Bibliographic Details
Main Authors: Mahita Razanakolona, Frédéric Adam, Elsa Bianchini, François Saller, Allan de Carvalho, Jean-Luc Diehl, Cécile V. Denis, Ferhat Meziani, Delphine Borgel, Julie Helms, Marc Vasse
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2021-04-01
Series:TH Open
Subjects:
protein z-dependent plasma protease inhibitor
proinflammatory cytokines
ccl5
lipopolysaccharide
monocytes
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1730037

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1730037

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