Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis

Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis

Synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins couple their stage-wise folding/assembly to rapid exocytosis of neurotransmitters in a Munc18-1-dependent manner. The functions of the different assembly stages in exocytosis and the role of Munc18-1 in SNARE ass...

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Bibliographic Details
Main Authors: Lu Ma, Aleksander A Rebane, Guangcan Yang, Zhiqun Xi, Yuhao Kang, Ying Gao, Yongli Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
SNARE assembly
munc18-1
membrane fusion
optical tweezers
synaptic exocytosis
energy landscape
Online Access:https://elifesciences.org/articles/09580

Internet

https://elifesciences.org/articles/09580

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