Evaluation of Drug Delivery and Efficacy of Ciprofloxacin-Loaded Povidone Foils and Nanofiber Mats in a Wound-Infection Model Based on Ex Vivo Human Skin

Evaluation of Drug Delivery and Efficacy of Ciprofloxacin-Loaded Povidone Foils and Nanofiber Mats in a Wound-Infection Model Based on Ex Vivo Human Skin

Topical treatment of wound infections is often a challenge due to limited drug availability at the site of infection. Topical drug delivery is an attractive option for reducing systemic side effects, provided that a more selective and sustained local drug delivery is achieved. In this study, a poorl...

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Bibliographic Details
Main Authors: Fiorenza Rancan, Marco Contardi, Jana Jurisch, Ulrike Blume-Peytavi, Annika Vogt, Ilker S. Bayer, Christoph Schaudinn
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Pharmaceutics
Subjects:
wound infection
biofilm
pseudomonas aeruginosa
antimicrobial delivery
polyvinylpyrrolidone
nanofibers
Online Access:https://www.mdpi.com/1999-4923/11/10/527

Internet

https://www.mdpi.com/1999-4923/11/10/527

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