SIDT2 RNA Transporter Promotes Lung and Gastrointestinal Tumor Development

Summary: RNautophagy is a newly described type of selective autophagy whereby cellular RNAs are transported into lysosomes for degradation. This process involves the transmembrane protein SIDT2, which transports double-stranded RNA (dsRNA) across the endolysosomal membrane. We previously demonstrate...

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Bibliographic Details
Main Authors: Tan A. Nguyen, Kathryn T. Bieging-Rolett, Tracy L. Putoczki, Ian P. Wicks, Laura D. Attardi, Ken C. Pang
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219303463