Social defeat during adolescence and adulthood differentially induce BDNF-regulated immediate early genes

Social defeat during adolescence and adulthood differentially induce BDNF-regulated immediate early genes

Stressful life events generally enhance the vulnerability for the development of human psychopathologies such as anxiety disorders and depression. The incidence rates of adult mental disorders steeply rises during adolescence in parallel with a structural and functional reorganization of the neural...

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Bibliographic Details
Main Authors: Caroline M. Coppens, Taweeporn eSiripornmongcolchai, Karin eWibrand, Maria eNordheim Alme, Bauke eBuwalda, Sietse F. De Boer, Jaap M. Koolhaas, Clive R. Bramham
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Hippocampus
adolescence
rat
stress
synaptic plasticity
Social Defeat
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00072/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00072/full

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