BRAF Alteration in Central and Peripheral Nervous System Tumors

BRAF (alternately referred to as v-raf murine sarcoma viral oncogene homolog B1) is a proto-oncogene involved in the mitogen-activated protein kinase (MAPK) pathway. BRAF alterations are most commonly missense mutations or aberrant fusions. These mutations are observed in numerous primary central ne...

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Bibliographic Details
Main Authors: Komal Srinivasa, Kevin A. Cross, Sonika Dahiya
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
CNS
PNS
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.574974/full