Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m

The high overexpression of cholecystokinin-2 receptors (CCK2R) in tumors, such as medullary thyroid carcinoma, allows for highly specific diagnostic and therapeutic targeting with radiolabeled peptide probes derived from natural ligands for the receptor. Based on the ideal imaging characteristics, h...

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Bibliographic Details
Main Authors: Maximilian Klingler, Christine Rangger, Dominik Summer, Piriya Kaeopookum, Clemens Decristoforo, Elisabeth von Guggenberg
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/12/1/13