Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography.

Extracellular vesicles (EVs) are a heterogeneous population of biological particles released by cells. They represent an attractive source of potential biomarkers for early detection of diseases such as cancer. However, it is critical that sufficient amounts of EVs can be isolated and purified in a...

Full description

Bibliographic Details
Main Authors: Eduarda M Guerreiro, Beate Vestad, Lilly Alice Steffensen, Hans Christian D Aass, Muhammad Saeed, Reidun Øvstebø, Daniela Elena Costea, Hilde Kanli Galtung, Tine M Søland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6160036?pdf=render