Quantitative Proteomics Analysis of FFPE Tumor Samples Reveals the Influences of NET-1 siRNA Nanoparticles and Sonodynamic Therapy on Tetraspanin Protein Involved in HCC

Quantitative Proteomics Analysis of FFPE Tumor Samples Reveals the Influences of NET-1 siRNA Nanoparticles and Sonodynamic Therapy on Tetraspanin Protein Involved in HCC

Hepatocellular carcinoma (HCC) poses a severe threat to human health. The NET-1 protein has been proved to be strongly associated with HCC proliferation and metastasis in our previous study. Here, we established and validated the NET-1 siRNA nanoparticles system to conduct targeted gene therapy of H...

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Bibliographic Details
Main Authors: Bolin Wu, Haitao Shang, Jiayin Liu, Xitian Liang, Yanchi Yuan, Yichi Chen, Chunyue Wang, Hui Jing, Wen Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
hepatocellular carcinoma
sonodynamic therapy
tetraspanin protein
mass spectrometry
proteomics
ultrasound
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.678444/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.678444/full

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