Role of a Transbilayer pH Gradient in the Membrane Fusion Activity of the Influenza Virus Hemagglutinin: Use of the R18 Assay to Monitor Membrane Merging

<p>It had been suggested that influenza virus-mediated membrane fusion might be dependent on a pH gradient across a target membrane. We have designed experiments in which this issue could be addressed. Two populations of liposomes were prepared, both simulating the plasma membrane of target ce...

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Bibliographic Details
Main Authors: Pedroso de Lima Maria C., Ramalho-Santos João
Format: Article
Language:English
Published: BMC 1999-01-01
Series:Biological Procedures Online
Subjects:
Online Access:http://www.biologicalprocedures.com/bpo/arts/1/13/m13.htm