Aged PROP1 deficient dwarf mice maintain ACTH production.

Humans with PROP1 mutations have multiple pituitary hormone deficiencies (MPHD) that typically advance from growth insufficiency diagnosed in infancy to include more severe growth hormone (GH) deficiency and progressive reduction in other anterior pituitary hormones, eventually including adrenocorti...

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Bibliographic Details
Main Authors: Igor O Nasonkin, Robert D Ward, David L Bavers, Felix Beuschlein, Amanda H Mortensen, Catherine E Keegan, Gary D Hammer, Sally A Camper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3228747?pdf=render