Anti-ganglioside antibodies alter presynaptic release and calcium influx

Anti-ganglioside antibodies alter presynaptic release and calcium influx

Acute motor axonal neuropathy (AMAN) variant of Guillain–Barré syndrome is often associated with IgG anti-GM1 and -GD1a antibodies. The pathophysiological basis of antibody-mediated selective motor nerve dysfunction remains unclear. We investigated the effects of IgG anti-GM1 and -GD1a monoclonal an...

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Bibliographic Details
Main Authors: Brigitte Buchwald, Gang Zhang, Angela K. Vogt-Eisele, Weiyi Zhang, Raheleh Ahangari, John W. Griffin, Hanns Hatt, Klaus V. Toyka, Kazim A. Sheikh
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Neurobiology of Disease
Subjects:
Guillain–Barré syndrome
AMAN
Anti-ganglioside antibodies
Gangliosides
Immune neuropathies
Neuromuscular junction
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001404

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http://www.sciencedirect.com/science/article/pii/S0969996107001404

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