How are base excision DNA repair pathways deployed in vivo? [version 1; referees: 4 approved]

Since the discovery of the base excision repair (BER) system for DNA more than 40 years ago, new branches of the pathway have been revealed at the biochemical level by in vitro studies. Largely for technical reasons, however, the confirmation of these subpathways in vivo has been elusive. We review...

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Bibliographic Details
Main Authors: Upasna Thapar, Bruce Demple
Format: Article
Language:English
Published: F1000 Research Ltd 2017-03-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-279/v1