A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria.

Cerebral Malaria (CM) is associated with a pathogenic T cell response. Mice infected by P. berghei ANKA clone 1.49 (PbA) developing CM (CM+) present an altered PBL TCR repertoire, partly due to recurrently expanded T cell clones, as compared to non-infected and CM- infected mice. To analyse the rela...

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Bibliographic Details
Main Authors: Encarnita Mariotti-Ferrandiz, Hang-Phuong Pham, Sophie Dulauroy, Olivier Gorgette, David Klatzmann, Pierre-André Cazenave, Sylviane Pied, Adrien Six
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4742225?pdf=render