Hypomethylation of MIR‐378 5’‐flanking region predicts poor survival in young patients with myelodysplastic syndrome

Hypomethylation of MIR‐378 5’‐flanking region predicts poor survival in young patients with myelodysplastic syndrome

Abstract Background Previous studies have disclosed up‐regulation of MIR‐378 in acute myeloid leukemia (AML), and might consequently affect the outcome of the patients. Correspondingly, hypomethylation of MIR‐378 was also identified in AML, particularly for FAB‐M2 subtype with t(8;21) chromosomal tr...

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Bibliographic Details
Main Authors: De‐hong Wu, Xiao‐wen Zhu, Xiang‐mei Wen, Ying‐ying Zhang, Ji‐chun Ma, Dong‐ming Yao, Jing‐dong Zhou, Hong Guo, Peng‐fei Wu, Xing‐li Zhang, Hong‐chun Qiu, Jiang Lin, Jun Qian
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
hypomethylation
MIR‐378
myelodysplastic syndrome
prognosis
Online Access:https://doi.org/10.1002/mgg3.1067

Internet

https://doi.org/10.1002/mgg3.1067

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