Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals.

Splice sites (SSs)--short nucleotide sequences flanking introns--are under selection for spliceosome binding, and adhere to consensus sequences. However, non-consensus nucleotides, many of which probably reduce SS performance, are frequent. Little is known about the mechanisms maintaining such appar...

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Bibliographic Details
Main Authors: Stepan Denisov, Georgii Bazykin, Alexander Favorov, Andrey Mironov, Mikhail Gelfand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0144388