Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome

<p>Abstract</p> <p>Background</p> <p>Human immunodeficiency virus type 1 (HIV-1) can be inhibited by means of RNA silencing or interference (RNAi) using synthetic short interfering RNAs (siRNAs) or gene constructs encoding short hairpin RNAs (shRNAs) or long hairpin RNA...

Full description

Bibliographic Details
Main Authors: Konstantinova Pavlina, ter Brake Olivier, Haasnoot Joost, de Haan Peter, Berkhout Ben
Format: Article
Language:English
Published: BMC 2007-03-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/15