SOX1 Is Required for the Specification of Rostral Hindbrain Neural Progenitor Cells from Human Embryonic Stem Cells

Summary: Region-specific neural progenitor cells (NPCs) can be generated from human embryonic stem cells (hESCs) by modulating signaling pathways. However, how intrinsic transcriptional factors contribute to the neural regionalization is not well characterized. Here, we generate region-specific NPCs...

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Bibliographic Details
Main Authors: Xinyuan Liu, Zhuoqing Fang, Jing Wen, Fan Tang, Bing Liao, Naihe Jing, Dongmei Lai, Ying Jin
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306672