Sulphite oxidase (SO) – a mitochondrial autoantigen as target for humoral and cellular immune reactions in primary sclerosing cholangitis

Sulphite oxidase (SO) – a mitochondrial autoantigen as target for humoral and cellular immune reactions in primary sclerosing cholangitis

Abstract Background In a recent study we had evidence that sulphite oxidase (SO) may be a relevant autoantigen in primary sclerosing cholangitis (PSC). Aim of the present study was, therefore, to analyse humoral and cellular immune-reactivity towards SO in these patients in more detail. Methods Sera...

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Bibliographic Details
Main Authors: Beate E. Preuß, Christoph P. Berg, Christoph Werner, Sandra Plankenhorn, Nisar P. Malek, Reinhild Klein
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Gastroenterology
Subjects:
Primary sclerosing cholangitis
Sulphite oxidase
Autoantibodies
Epitope mapping
Cellular immune reactivity
Online Access:http://link.springer.com/article/10.1186/s12876-018-0787-x

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http://link.springer.com/article/10.1186/s12876-018-0787-x

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