Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

Summary: Regulatory T cells (Tregs) express high levels of cell surface lymphotoxin alpha beta (LTα1β2) to activate the LT beta receptor (LTβR) on the lymphatic endothelial cells (LECs), modulating LEC adhesion molecules, intercellular junctions, and chemokines. We demonstrate a role for Tregs throu...

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Bibliographic Details
Main Authors: Wenji Piao, Yanbao Xiong, Lushen Li, Vikas Saxena, Kile D. Smith, Keli L. Hippen, Christina Paluskievicz, Marina Willsonshirkey, Bruce R. Blazar, Reza Abdi, Jonathan S. Bromberg
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719317486

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http://www.sciencedirect.com/science/article/pii/S2211124719317486

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