Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration
Summary: Regulatory T cells (Tregs) express high levels of cell surface lymphotoxin alpha beta (LTα1β2) to activate the LT beta receptor (LTβR) on the lymphatic endothelial cells (LECs), modulating LEC adhesion molecules, intercellular junctions, and chemokines. We demonstrate a role for Tregs throu...
Main Authors: | Wenji Piao, Yanbao Xiong, Lushen Li, Vikas Saxena, Kile D. Smith, Keli L. Hippen, Christina Paluskievicz, Marina Willsonshirkey, Bruce R. Blazar, Reza Abdi, Jonathan S. Bromberg |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719317486 |
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