Heterologous Expression of Rhizopus Oryzae CYP509C12 Gene in Rhizopus Nigricans Enhances Reactive Oxygen Species Production and 11α-Hydroxylation Rate of 16α, 17-Epoxyprogesterone

The 11α-hydroxylation of 16α, 17-epoxyprogesterone (EP) catalyzed by Rhizopus nigricans is crucial for the steroid industry. However, lower conversion rate of the biohydroxylation restricts its potential industrial application. The 11α-steroid hydroxylase CYP509C12 from R. oryzae were reported to pl...

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Bibliographic Details
Main Authors: Chaohui Shen, Xiyang Gao, Tao Li, Jun Zhang, Yuqian Gao, Liyou Qiu, Guang Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-07-01
Series:Mycobiology
Subjects:
Online Access:http://dx.doi.org/10.1080/12298093.2019.1630201