Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses.

H3N2 influenza viruses have now circulated in the human population for 43 years since the pandemic of 1968, accumulating sequence changes in the hemagglutinin (HA) and neuraminidase (NA) that are believed to be predominantly due to selection for escape from antibodies. Examination of mutations that...

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Bibliographic Details
Main Authors: Lyubov Popova, Kenneth Smith, Ann H West, Patrick C Wilson, Judith A James, Linda F Thompson, Gillian M Air
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3405050?pdf=render