Pro-inflammatory and proliferative microglia drive progression of glioblastoma

Pro-inflammatory and proliferative microglia drive progression of glioblastoma

Summary: Scant understanding of the glioblastoma microenvironment and molecular bases hampers development of efficient treatment strategies. Analyses of gene signatures of human gliomas demonstrate that the SETD2 mutation is correlated with poor prognosis of IDH1/2 wild-type (IDH-WT) adult glioblast...

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Bibliographic Details
Main Authors: Hailong Liu, Youliang Sun, Qian Zhang, Wei Jin, Renata E. Gordon, Yanyang Zhang, Jian Wang, Caihong Sun, Zeyuan John Wang, Xueling Qi, Junping Zhang, Boyuan Huang, Qiuping Gui, Hongyu Yuan, Ling Chen, Xiaodong Ma, Chuan Fang, Yong-qiang Liu, Xinguang Yu, Shiyu Feng
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011670

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http://www.sciencedirect.com/science/article/pii/S2211124721011670

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