In vitro Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization

In vitro Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization

Vascular disruption following spinal cord injury (SCI) decisively contributes to the poor functional recovery prognosis facing patients with the condition. Using a previously developed gellan gum hydrogel to which the adhesion motif GRGDS was grafted (GG-GRGDS), this work aimed to understand the abi...

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Bibliographic Details
Main Authors: Luís A. Rocha, Eduardo D. Gomes, João L. Afonso, Sara Granja, Fatima Baltazar, Nuno A. Silva, Molly S. Shoichet, Rui A. Sousa, David A. Learmonth, Antonio J. Salgado
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
vascularization
spinal cord injury
neurovascular
biomaterial
cell therapy
secretome
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00489/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00489/full

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