Deficiency of COX7RP, a mitochondrial supercomplex assembly promoting factor, lowers blood glucose level in mice

Abstract Mitochondria are essential organelles to efficiently produce ATP by ATP-synthase, which uses a proton-gradient generated by respiratory chain complexes. We previously demonstrated that COX7RP/COX7A2L/SCAF1 is a key molecule that promotes respiratory supercomplex assembly and regulates energ...

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Bibliographic Details
Main Authors: Sachiko Shiba, Kazuhiro Ikeda, Kuniko Horie-Inoue, Akitoshi Nakayama, Tomoaki Tanaka, Satoshi Inoue
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08081-z