Safety and Efficacy of Roxadustat for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis

Safety and Efficacy of Roxadustat for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis and Trial Sequential Analysis

Background: Roxadustat, a hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI), has been used to treat anemia in patients with chronic kidney disease (CKD). However, its safety and efficacy remain controversial.Methods: The PubMed, EMBASE, Science Citation Index, Cochrane Central Register...

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Bibliographic Details
Main Authors: Chao Liu, Zhangning Fu, Jiawei Jiang, Kun Chi, Xiaodong Geng, Zhi Mao, Chengcheng Song, Guannan Sun, Quan Hong, Guangyan Cai, Xiangmei Chen, Xuefeng Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
Subjects:
roxadustat
anemia
chronic kidney disease
meta-analysis
trial sequential analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.724456/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.724456/full

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