Nischarin regulates focal adhesion and Invadopodia formation in breast cancer cells

Abstract Background During metastasis, tumor cells move through the tracks of extracellular matrix (ECM). Focal adhesions (FAs) are the protein complexes that link the cell cytoskeleton to the ECM and their presence is necessary for cell attachment. The tumor suppressor Nischarin interacts with a nu...

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Bibliographic Details
Main Authors: Mazvita Maziveyi, Shengli Dong, Somesh Baranwal, Suresh K. Alahari
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-018-0764-6