Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock.

Molecular genetic studies in the circadian model organism Synechococcus have revealed that the KaiC protein, the central component of the circadian clock in cyanobacteria, is involved in activation and repression of its own gene transcription. During 24 hours, KaiC hexamers run through different pho...

Full description

Bibliographic Details
Main Authors: Stefanie Hertel, Christian Brettschneider, Ilka M Axmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3597532?pdf=render