The Role of Apelin in Cardiovascular Diseases, Obesity and Cancer

Apelin is an endogenous peptide identified as a ligand of the G protein-coupled receptor APJ. Apelin belongs to the family of adipokines, which are bioactive mediators released by adipose tissue. Extensive tissue distribution of apelin and its receptor suggests, that it could be involved in many phy...

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Bibliographic Details
Main Authors: Marta B. Wysocka, Katarzyna Pietraszek-Gremplewicz, Dorota Nowak
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00557/full