Quantitative methylation level of the EPHX1 promoter in peripheral blood DNA is associated with polycystic ovary syndrome.

Steroid synthesis and metabolic pathways play important roles in the pathophysiology of PCOS, but until now there have been no studies on the methylation profiles of specific genes in steroid synthesis pathways that are known to be associated with PCOS. Here we used MassARRAY quantitative methylatio...

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Bibliographic Details
Main Authors: Qing Sang, Xin Li, Haojue Wang, Huan Wang, Shaozhen Zhang, Ruizhi Feng, Yao Xu, Qiaoli Li, Xinzhi Zhao, Qinghe Xing, Li Jin, Lin He, Lei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914883?pdf=render