Dominant immunosuppression of dendritic cell function by prostate-cancer-derived exosomes

Exosomes are a distinct population of extracellular vesicles of endocytic origin with a protein repertoire similar to the parent cell. Although tumour-derived exosomes harbour immunosuppressive characteristics, they also carry tumour antigens and thus potentially contribute to immune activation. The...

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Bibliographic Details
Main Authors: Josephine Salimu, Jason Webber, Mark Gurney, Saly Al-Taei, Aled Clayton, Zsuzsanna Tabi
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:http://dx.doi.org/10.1080/20013078.2017.1368823