Polycomb chromobox Cbx2 enhances antiviral innate immunity by promoting Jmjd3-mediated demethylation of H3K27 at the Ifnb promoter

Polycomb chromobox Cbx2 enhances antiviral innate immunity by promoting Jmjd3-mediated demethylation of H3K27 at the Ifnb promoter

Abstract Polycomb chromobox (CBX) proteins regulate gene transcription by maintaining chromatin states, which guide a variety of biological processes. Now, epigenetic regulation of innate immune response is an emerging field. However, the role of CBX proteins in innate immunity remains unclear. We c...

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Bibliographic Details
Main Authors: Donghao Sun, Xuetao Cao, Chunmei Wang
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:Protein & Cell
Subjects:
Cbx2
Jmjd3
interferon beta
innate immunity
Online Access:http://link.springer.com/article/10.1007/s13238-018-0581-0

Internet

http://link.springer.com/article/10.1007/s13238-018-0581-0

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