RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer

RRM2 protects against ferroptosis and is a tumor biomarker for liver cancer

Abstract Background Ferroptosis is the process of cell death triggered by lipid peroxides, and inhibition of glutathione (GSH) synthesis leads to ferroptosis. Liver cancer progression is closely linked to ferroptosis suppression. However, the mechanism by which inhibition of GSH synthesis suppresses...

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Bibliographic Details
Main Authors: Yueyue Yang, Jiafei Lin, Susu Guo, Xiangfei Xue, Yikun Wang, Shiyu Qiu, Jiangtao Cui, Lifang Ma, Xiao Zhang, Jiayi Wang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Cancer Cell International
Subjects:
GSS
Proteasome
Diagnosis
Phosphorylation
Glutathione
Erastin
Online Access:https://doi.org/10.1186/s12935-020-01689-8

Internet

https://doi.org/10.1186/s12935-020-01689-8

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