Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer

<p>Abstract</p> <p>Background</p> <p>Costimulatory signaling has been implicated as a potential regulator of antitumor immunity in various human cancers. In contrast to the negative prognostic value of aberrant B7-H1 expression by pancreatic cancer cells, the role of B7...

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Bibliographic Details
Main Authors: Kleeff Jörg, Esposito Irene, Laschinger Melanie, Giese Nathalia A, Ottenhausen Malte, Hedderich Dennis M, Loos Martin, Friess Helmut
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/463