BMP-2-coated mineral coated microparticles improve bone repair in atrophic non-unions

BMP-2-coated mineral coated microparticles improve bone repair in atrophic non-unions

Atrophic non-unions are a major clinical problem. Mineral coated microparticles (MCM) are electrolyte-coated hydroxyapatite particles that have been shown in vitro to bind growth factors electrostatically and enable a tuneable sustained release. Herein, we studied whether MCM can be used in vivo to...

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Bibliographic Details
Main Authors: M Orth, NJ Kruse, BJ Braun, C Scheuer, JH Holstein, A Khalil, X Yu, WL Murphy, T Pohlemann, MW Laschke, MD Menger
Format: Article
Language:English
Published: AO Research Institute Davos 2017-01-01
Series:European Cells & Materials
Subjects:
Non-union
mineral coated microparticles
BMP-2
bone healing
biocompatibility
mice
Online Access:http://www.ecmjournal.org/papers/vol033/pdf/v033a01.pdf

Internet

http://www.ecmjournal.org/papers/vol033/pdf/v033a01.pdf

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