Clinical and genetic factors associated with increased risk of severe liver toxicity in a monocentric cohort of HIV positive patients receiving nevirapine-based antiretroviral therapy

Clinical and genetic factors associated with increased risk of severe liver toxicity in a monocentric cohort of HIV positive patients receiving nevirapine-based antiretroviral therapy

Abstract Background Nevirapine has been used as antiretroviral agent since early ‘90. Although nevirapine is not currently recommended in initial anti-HIV regimens, its use remains consistent in a certain number of HIV-1-positive subjects. Thus, our aim was to determine clinical and genetic factors...

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Bibliographic Details
Main Authors: Andrea Giacomelli, Agostino Riva, Felicia Stefania Falvella, Maria Letizia Oreni, Dario Cattaneo, Stefania Cheli, Giulia Renisi, Valentina Di Cristo, Angelica Lupo, Emilio Clementi, Stefano Rusconi, Massimo Galli, Anna Lisa Ridolfo
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Infectious Diseases
Subjects:
Nevirapine
Pharmacogenetic
Hepatotoxicity
ABCB1
Online Access:http://link.springer.com/article/10.1186/s12879-018-3462-5

Internet

http://link.springer.com/article/10.1186/s12879-018-3462-5

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