Rabeprazole inhibits inflammatory reaction by inhibition of cell pyroptosis in gastric epithelial cells

Rabeprazole inhibits inflammatory reaction by inhibition of cell pyroptosis in gastric epithelial cells

Abstract Background Helicobacter pylori (H. pylori) is a common pathogen in development of peptic ulcers with pyroptosis. Rabeprazole, a critical component of standard triple therapy, has been widely used as the first-line regimen for H. pylori infectious treatment. The aim of this study to explore...

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Bibliographic Details
Main Authors: Jing Xie, Long Fan, Liya Xiong, Peiyu Chen, Hongli Wang, Huan Chen, Junhong Zhao, Zhaohui Xu, Lanlan Geng, Wanfu Xu, Sitang Gong
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
Rabeprazole
NLRP3
GSDMD
Cell pyroptosis
H. pylori infection
Online Access:https://doi.org/10.1186/s40360-021-00509-7

Internet

https://doi.org/10.1186/s40360-021-00509-7

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